![Mystic, CT - 11/18/2018- ] William Korinek, CEO of Astrocyte Pharmaceuticals, plays tag football at ST Butler Elementary School in Mystic with his two sons and longtime friends on Sunday, November 19, 2018. Korinek and Astrocyte Pharmaceuticals are now developing a drug to treat concussions. (Michael Swensen for The Boston Globe) Topic: (business)](www_bostonglobe_com/rf/image_r/Boston/2011-2020/2018/11/19/BostonGlobe.com/Business/Images/swensen18111815concussiondrugs-0005.r.jpg)
Michael Swensen for The Boston Globe
A number of start-ups are experimenting with drugs that could be taken immediately after blunt head trauma in the hope of preventing or limiting damage.
Boston Cardinal Sean O?Malley was notably absent from the organizing committee lineup preparing for a high-stakes summit on abuse prevention.
Dejon Barnes and Kenneth Ford were charged with murdering 18-year-old Kemoni Miller, who died in a hospital Wednesday after four days on life support.
The mercury dipped to 7 degrees in Worcester, which broke the old record of 9 degrees set in 1989.
Think it?s cold where you are? Check Mount Washington Weather observers recorded a record low of -26 degrees early Thursday with hurricane force winds that dropped the windchill down to -75 degrees.
Trump says it?s time for action on ?the Wall? President Donald Trump began his Friday on Twitter saying Democrats and Republicans ?MUST come together? on border security and ?funding for the Wall.?
?Extreme cold and wind created many problems,? said Lowell Fire Chief Jeffrey Winward. ?Frozen hose lines, frozen ladder pipes, the entire neighborhood was covered in ice.?
Lynn Fire Department
Two firefighters sustained minor injuries while battling the flames, Lynn Fire Chief Stephen Archer said.
David L. Ryan/Globe Staff
The latest hydroelectric plan ? routing Canadian power through Maine ? faces growing opposition, threatening a cornerstone of Governor Charlie Baker?s energy policy.
Dozens of sea turtles died in Cape Cod?s cold waters More than 150 turtles were found dead or immobile on beaches in the mid-Cape Wednesday and Thursday as temperatures fell overnight.
Kevin Winter/Getty Images
Commentary | Jeneé Osterheldt
In Boston this weekend for her book tour, Michelle Obama is entering a superstar status reserved for the likes of Beyoncé. And some people can?t get over it.
CHAD FINN | SPORTS MEDIA
?Monday Night Football? has a big problem: Jason Witten The novice analyst has been gaffe-prone, but ratings are up and ESPN is standing by its first-year team.
NAMES
Breakout star Florence Pugh talks about filming ?Little Women? around Boston The actress is part of an all star cast filming in the area, including Meryl Streep, Emma Watson, Saoirse Ronan, and Timothée Chalamet.
NAMES
Reporter and anchor Sorboni Banerjee takes on fiction in her debut novel, ?Hide With Me? The former Boston news anchor, now based in Florida, has her first book out now.
Gary Washburn | On Basketball
Celtics are angry, they are not playing hard, and trust is a major issue Players are unhappy with a lack of playing time and unhappy when they are playing, and it all adds up to one big mess.
Jessica Rinaldi/Globe Staff/File
Capital Source
After failing to generate much attention as a candidate beyond media curiosity and online fame, Brianna Wu is looking ahead. ?I?m focused on 2020. I?m going to win this time,? Wu said this week.
Pablo Martinez Monsivais/Associated Press
Editorial
Democrats must make it clear that they will demand information about all interactions Acting Attorney General Matthew Whitaker has with the Special Counsel?s office
Zach Gibson/Getty Images
Stephen Kinzer
Three new books take on a self-satisfied establishment whose ideas have destabilized the world and undermined our national security.
COOKING | MAGAZINE
Thanksgiving leftovers? Try this turkey Reuben recipe Save some leftover Thanksgiving turkey for a variation on a classic Reuben sandwich accompanied by an unusual ? and unusually good ? slaw.
Miss Conduct
Advice: How to say ?No presents, please? My large extended family loves to give gifts but I don?t have the room for them.
Vermont couple looking for family peacock that ran off with turkeys The peacock has been on the run for six weeks after seeking out its new turkey companions.
Globe Magazine
Help was a few feet away. Why didn?t they save her? My wife, Laura Levis, did everything she could to save herself when the asthma attack began. She went to Somerville Hospital and called 911, too. How could she have been left to die just outside the emergency room?
Subscribe to This Week in Weed Witness the birth of the marijuana industry in Massachusetts, and catch up on national pot headlines. Subscribe to ?This Week in Weed? for the latest marijuana news from reporter Dan Adams every Saturday.
JOSH EDELSON/AFP/Getty Images
The Big Picture
At least 79 people have lost their lives in California?s deadliest wildfire.
?Meant no disrespect to the Holiday and those who celebrate it respectfully,? Irving tweeted Thursday morning.
Scores of people came together to make Thanksgiving a reality for the many families still struggling after gas fires and explosions in the region.
Forget the high-end kitchen. A new status symbol is zooming onto the domestic landscape: the luxury garage.
Incensed by a ruling against his migrant asylum policy, President Trump demanded ?common sense? from judges.
Patty Rough lost her Paradise home and most of her belongings in the Camp Fire, and she had no place to cook a family meal on Thanksgiving.
Search This Week's Specials
The four-door coupe has matured, and it pushes the limits of driving elegance.
Partners is the state?s largest private employer, so its policies are watched by other companies in health care and other fields.
The Globe?s picks for the best ways to spend your weekend.
As the city of Boston cheered on the Sox at the World Series parade, the cast of ?Little Women? quietly filmed scenes a few miles south in Harvard?s Arnold Arboretum.
Sixty years later, Mom?s Christmas tablecloth captures our family history.
Single-cell sequencing is opening up new avenues for potential treatments By quickly analyzing thousands of cells, it?s now possible to visualize the specific cellular culprits for any given disease.
Until next year, my sweetheart In a special bonus episode, Meredith Goldstein explores what happens to summer romance when the summer ends, and ?Wet Hot American Summer? creator David Wain shares a girl-crazy memory from his own camp days.
Listen: Apple Podcasts | Stitcher | RadioPublic
Are we ignoring ? or outright banning ? an easy affordable-housing fix? Mobile homes may be the least expensive and most effective means of addressing the region?s housing shortage.
