In the biotech hurly-burly, a cautionary tale

Bill Brett for The Boston Globe

For the CEO of a biotech startup, there may be no bigger asset than a compelling sales pitch. Frank Reynolds had a great one.

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2018/09/08/BostonGlobe.com/Metro/Images/Rex_Senate_reaction_to_Manafort_conv_9799440AG.jpg Sen. Collins mum on Kavanaugh vote as pressure grows

If Susan Collins votes yes, then Brett Kavanaugh is likely confirmed.

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2018/09/08/BostonGlobe.com/Metro/Images/AFP_18X9WN.jpg Trump says Apple can avoid tariffs by shifting production to US

President Trump concedes that some Apple Inc. products may become more expensive if his administration imposes ??massive?? additional tariffs on Chinese-made goods.

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2018/09/08/BostonGlobe.com/National/Images/58bbd66bbe82440e81299a23936058c6-58bbd66bbe82440e81299a23936058c6-0.jpg For Sessions, Trump?s constant attacks may define his legacy

Attorney General Jeff Sessions has pushed President Trump?s agenda at the Justice Department.

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2018/09/08/BostonGlobe.com/Metro/Images/1029409926.jpg Obama, on campaign swing, urges ?sanity in our politics?

Former president Barack Obama didn?t mention President Trump by name during a 20-minute speech on Saturday.

 Massachusetts Republican gubernatorial candidate Charlie Baker speaks to supporters during his primary election night victory rally Tuesday, Sept. 9, 2014 in Boston. Baker will face state Attorney General Martha Coakley in the Nov. 4, 2014 general election. (AP Photo/Stephan Savoia)

AP Photo/Stephan Savoia

EDITORIAL

Charlie Baker: Four years later

Four years after endorsing Charlie Baker, the editorial board reflects on how 2014 priorities can inform the 2018 election.

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2018/04/12/BostonGlobe.com/Sports/Images/lee_041118_celticsnets1_met.jpg Celtics player Jabari Bird is arrested after alleged ?domestic incident?

Celtics shooting guard Jabari Bird was arrested in Brighton Friday after a ?domestic incident? in which he allegedly assaulted, strangled, and kidnapped somebody, according to Boston police.

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2018/09/07/BostonGlobe.com/Metro/Images/ryan_gallardo2_met.jpg Driver who allegedly ran over Cambridge woman called 911, drove away, prosecutors say

Ashley A. Monturio, 41, was arraigned Friday for allegedly driving over Romelia Gallardo in a Cambridge parking lot, calling 911, and then fleeing the scene.

Manchester, NH - 8/30/2018 - Cathy Merrill during a

Barry Chin/Globe Staff

THOMAS FARRAGHER

N.H. woman beats the odds in arm wrestling

What happened one day at the Cornish Fair has led a 53-year-old New Hampshire native around the world and to the top of the arm-wrestling world.

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2018/09/08/BostonGlobe.com/National/Images/9e547fc856804e49b2cfeb37b859e663-9e547fc856804e49b2cfeb37b859e663-0.jpg Mother wonders if race factored into shooting death by officer of son in his Dallas apartment

The mother of a black Caribbean man who was fatally shot by a white Dallas police officer who said she mistook his apartment for her own wonders whether her son?s race was a factor in his killing.

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2018/09/08/BostonGlobe.com/National/Images/5f8f33b9406e4fefbc420e7ee5771b86-5f8f33b9406e4fefbc420e7ee5771b86-0.jpg Pope tells bishops to fight abuse, culture behind it

Pope Francis told newly ordained bishops Saturday that they must reject all forms of abuse.

Saugus High School football coach placed on leave

Police have launched an investigation over a team-related incident that occurred in late August, officials said Saturday.

Minneapolis, MN - 2/4/2018 - The Patriots bench is not a happy place in the fourth quarter, including quarterback Tom Brady (12) and some of his teammates, including Danny Amendola (80), and Rob Gronkowski in the backround during Super Bowl LII. The New England Patriots play the Philadelphia Eagles in Super Bowl LII at US Bank Stadium in Minneapolis on Feb. 4, 2018. (Jim Davis/Globe staff

FILE/JIM DAVIS/GLOBE STAFF

BEN VOLIN I ON FOOTBALL

Will losing Super Bowl have a lasting effect on Patriots?

The last team to get back to the Super Bowl the year after losing it was the early ?90s Bills.

Boston, MA - 8/09/2018 - (2nd quarter) New England Patriots quarterback Tom Brady (12) and New England Patriots tight end Rob Gronkowski (87) did not play. The New England Patriots host the Washington Redskins in a pre-season exhibition game at Gillette Stadium. - (Barry Chin/Globe Staff), Section: Sports, Reporter: James M. McBride, Topic: 10Patriots-Redskins, LOID: 8.4.2791165379.

CHAD FINN

The age-old question: How good can Tom Brady be this year?

?He?s not beating Father Time, but he is capable of keeping the lead longer than any of the rest of us ever could,? analyst Tony Romo said.

Palm trees frame a large billboard on top of a Nike store that shows former San Francisco 49ers quarterback Colin Kaepernick at Union Square, Wednesday, Sept. 5, 2018, in San Francisco. An endorsement deal between Nike and Colin Kaepernick prompted a flood of debate Tuesday as sports fans reacted to the apparel giant backing an athlete known mainly for starting a wave of protests among NFL players of police brutality, racial inequality and other social issues. (AP Photo/Eric Risberg)

Kevin Paul Dupont | On Second Thought

Let?s look at the impact of the Nike ad featuring Colin Kaepernick

Kaepernick, now 30, can?t find work, and it?s obvious his decision to take a knee all but booted away his career.

New England Patriots quarterback Tom Brady, right, holds the AFC championship trophy beside team owner Robert Kraft, left, honorary captain Tedy Bruschi, second from left, and head coach Bill Belichick after the AFC championship NFL football game, Sunday, Jan. 22, 2017, in Foxborough, Mass. The New England Patriots defeated the the Pittsburgh Steelers 36-17 to advance to the Super Bowl. (AP Photo/Matt Slocum)

TARA SULLIVAN

When will the Patriots? dominance end? Probably not this year

As the rest of the NFL wondering how long this can last, the signs point to another season of excellence.

PHILADELPHIA, PA - SEPTEMBER 2: Jon Lester #34 of the Chicago Cubs throws a pitch in the bottom of the fifth inning against the Philadelphia Phillies at Citizens Bank Park on September 2, 2018 in Philadelphia, Pennsylvania. (Photo by Mitchell Leff/Getty Images)

NICK CAFARDO | SUNDAY BASEBALL NOTES

A Red Sox-Cubs World Series would be the perfect end to the season

The two storied franchises appear to be on a collision course to the Fall Classic.

Gary Washburn | On basketball

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2018/09/08/BostonGlobe.com/Sports/Images/lee_090718_nbahof14_spts.jpg The old Celtics Ubuntu was back as Ray Allen joined hall of fame

Danny Ainge, the architect of the 2008 championship team, was on hand as Allen was inducted along with ex-Celtics Charlie Scott and Dino Radja.

Opinion | Alan M. Dershowitz

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2018/09/07/BostonGlobe.com/EditorialOpinion/Images/AFP_18X8ZG.jpg Donald Trump is not an unindicted coconspirator

Those who misuse the term should stop. And when they persist, they should be corrected.

India hunts man-eating tiger blamed for 13 deaths

The first victim was an older woman, discovered facedown in a cotton field with huge claw marks dug into her back. The next was an older male farmer, his left leg torn off.

Raymond So (left), a sophomore at Harvard, and Charles Czeisler, professor of sleep medicine, talked to freshmen about the importance of sleep and the lack thereof on the Harvard campus last month.

Michael Swensen for The Boston Globe

Many college students don?t sleep well. This Harvard course hopes to change that

Freshmen are now required to take an online course about sleep before they arrive on campus, part of a new initiative to help students have healthier sleep habits.

JEFF JACOBY

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2018/09/06/BostonGlobe.com/Ideas/Images/jacoby-1623.jpg Celebrity gossip may be entertaining, but it makes our whole culture sick

Sticks and stones may break our bones, but words ? ugly, gossipy, cruel words ? can eventually break a whole society.

BC 62, HOLY CROSS 14

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2018/09/08/BostonGlobe.com/Sports/Images/7ba3ff1a64a34bdbb7a1deaa0868265a-7ba3ff1a64a34bdbb7a1deaa0868265a-0.jpg BC football routs Holy Cross

The Eagles? starting backfield called it a day after 12 plays from scrimmage.

US Open

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2018/09/08/BostonGlobe.com/Sports/Images/AFP_18Y75V.jpg Serena Williams pays dearly in losing US Open championship to Naomi Osaka

Williams penalized a game late in the second set for unsportsmanlike conduct.

This image released by Fox Searchlight shows Robert Redford in a scene from the film,

A range of films at Toronto, including Robert Redford?s latest

The Toronto Interational Film Festival features movies from across genres and countries, among them a new film starring Robert Redford.

Cardi B escorted out of fashion party after lunging at Nicki Minaj

Nicki Minaj and Cardi B were involved in an altercation Friday night that got physical at a New York Fashion Week party.

Ceviche mixto at Celeste.

Dining Out

The Somerville restaurant that?s more like a dinner party

You?ll find ceviche, pisco sours, and a community of artists at Peruvian spot Celeste.

Opinion & Ideas

Editorial

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2018/09/07/BostonGlobe.com/Metro/Images/ryan_backschool4_met[1].jpg Blame for late school buses goes round and round

In the absence of effective mayoral leadership, the city council or the school committee may need to flex their muscles.

Nation & World

Tags in this section:

President Donald Trump's Supreme Court nominee, Brett Kavanaugh readies his papers before he testifies before the Senate Judiciary Committee on Capitol Hill in Washington, Thursday, Sept. 6, 2018, for the third day of his confirmation to replace retired Justice Anthony Kennedy. (AP Photo/Alex Brandon)

Senate concludes Kavanaugh hearing; confirmation likely

Senate Democrats had worked into the night Thursday on Brett Kavanaugh?s final day of questioning in a last, ferocious attempt to paint him as a foe of abortion rights and a likely defender of President Trump.

Arts

Dancers during a dress rehearsal of the Boston Ballet production of ?Genius at Play? at the Opera House.

Dance Review

Boston Ballet kicks up its heels in ?Genius at Play?

Boston Ballet?s season opener, ?Genius at Play,? celebrates the centennial of Jerome Robbins, who was most certainly a genius and also the greatest choreographer America has produced.

Love Letters: The Podcast

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2018/08/29/BostonGlobe.com/Lifestyle/Images/200_love_letters_bonus.jpg Until next year, my sweetheart

In a special bonus episode, Meredith Goldstein explores what happens to summer romance when the summer ends, and ?Wet Hot American Summer? creator David Wain shares a girl-crazy memory from his own camp days.

Listen:   Apple Podcasts   |   Stitcher   |   RadioPublic

 

Real Estate

Address

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2018/04/06/BostonGlobe.com/Lifestyle/Images/stan-fellows-home-nest-illustration$medium.jpg Spring House Hunt: Should parents buy property in a college town?

As the spring house hunt gets underway and National College Decision Day nears, thoughts are turning to campus housing.

Globe event

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2018/06/08/BostonGlobe.com/Business/Images/SeattleTimes_10kirsner02_biz.jpg Seattle?s mayor talks growing pains that offer some lessons for Boston

Seattle mayor Jenny Durkan spoke at a Globe event on how innovation is shaping our world, and she?s in high demand among the hundreds of mayors gathered in Boston.

Podcast

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2018/07/18/BostonGlobe.com/Arts/Images/FlfQGTy9_585.jpg More about Last Seen: The Largest Unsolved Art Heist ever

A true-crime podcast about the most valuable ? and confounding ? art heist in history: the theft of 13 irreplaceable artworks from the Isabella Stewart Gardner Museum in Boston.

The Big Picture

Craig F. Walker/Globe Staff

The Big Picture

Globe staff photos of the month, August 2018

Here?s a look at some of the best images taken by Globe photographers last month: staying cool in the summer heat, installing a new police commissioner, spotting sharks on the Cape, campaigning politicians on the trail, and flipping gymnasts at the US championships.

Crossword

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2017/08/21/BostonGlobe.com/Business/Images/crossword.jpg Play the crossword

Puzzled? Keep trying your hand at our interactive crossword and see if you can triumph.