This Cambridge nonprofit is seeking every drug ever developed

A vial of a compound inside a lab at the Broad Institute of MIT and Harvard.

Jonathan Wiggs/Globe Staff

A local biomedical institute wants to see if drugs can be used to treat diseases besides those for which they were intended.

// 1 person killed, four injured in Paris knife attack, police say

French authorities say a knife-wielding assailant killed one person and injured four in the center of Paris before being killed by police.

// Boston battles three fires, including six-alarm blaze in West Roxbury

Three non-life-threatening injuries were reported at a large multi-unit apartment building in the West Roxbury fire, which was fueled by a gas leak, officials said.

// New sexual abuse lawsuit filed against St. Paul?s School

A former student alleges the New Hampshire boarding school failed to protect her from sexual assault and harassment under federal law.

// After a rainy Saturday, sun is expected for Mother?s Day

Highs on Sunday are expected to be in the upper 50s in the afternoon as the sun breaks through, according to the National Weather Service.

// Amid a swirl of investigations, Devin Nunes takes on the Justice Department

Representative Devin Nunes has become a fierce critic of the Justice Department as it conducts investigations with a possible connection to the Trump White House.

Clashing views on Iran reflect a new balance of power in the cabinet

The frantic final days before the president?s announcement demonstrate that the Iran deal remained a complicated, divisive issue inside the White House.

// Missing for 48 hours: Pentagon details Army sergeant?s final moments in Niger

No figure in the ambush in Niger has commanded more attention than US Army Sgt. La David T. Johnson.

Tom Brenner/The New York Times

Second Democrat announces support for CIA nominee Haspel

Gina Haspel?s nomination to be CIA director received a crucial boost Saturday.

// Israel bombs Gaza tunnel, closes key crossing after attack

The Israeli military said Saturday it was shutting down its main cargo crossing into Gaza.

Boston04/12/18 Stanley Cup Playoffs- Bruins vs Maple Leafs- Bruins David Backes celebrates his 2nd period goal with the fans. Photo by John Tlumacki/Globe Staff(sports)

John Tlumacki/Globe Staff


David Backes and the balance of weighing concussion history against a career

Backes knows the science, and he knows his history and his age, and above all he knows the inherent risks of concussions.


// Should mentoring be part of an NFL quarterback?s job description?

Players are supposed to be teammates, but are fighting with each other for one of 53 precious roster spots.


// These Celtics have rewritten the laws of title contention in the NBA

?Next man up? isn?t supposed to work in the NBA postseason. But Boston is making it happen.

Baltimore Orioles manager Buck Showalter, second from left, talks with catcher Caleb Joseph, left, during a pitching change against the Detroit Tigers in the seventh inning of baseball game, Saturday, April 28, 2018, in Baltimore. (AP Photo/Gail Burton)


How the Orioles became the most dysfunctional organization in baseball

There have been reports that GM Dan Duquette has been ?thrown out of the cockpit,? but no one knows who?s flying the plane.


// Getting rid of cheerleading is not the solution for the NFL

Taking aim at the women rather than their bosses further punishes the victims.

Nestor Ramos

// ?NotDavidPrice? tried ?Fortnite? for first time to figure out the hoopla. It didn?t go well

Video games have been catching the blame for just about everything for decades. David Price can probably relate.

Renée Graham

// Axl Rose ? a small, hopeful example for our fractured nation?

A reissue from Guns N? Roses leaves out ?One In A Million,? which denounced African-Americans, immigrants, and gay men.

Lane Turner/Globe Staff

Starts & Stops

State Senate backs study on electrification of T rail system

The chamber?s proposed budget would set the stage for the T to run electric service on two commuter lines.

Pan-fried fresh salmon cakes, spring herb and prosciutto omelet, and remoulade sauce.

Cooking | Magazine

Recipes: An easy, elegant feast for Mother?s Day brunch

Surprise her this year with an elegant feast that sounds fancy but is simpler than you?d think to prepare.

// Closing time comes for Allston neighborhood pub

After 38 years, the Bus Stop Pub will close Saturday.

Boston, MA., 05/04/18, Northeastern University holds its commencement at the TD Garden. Graduation speaker Aimee Mullins gets her hood. Suzanne Kreiter/Globe staff

Your guide to local college graduations

Here is a look at this season?s graduation schedule and some of the notable speakers at colleges around the region.

// Boston Dynamics posts video of jogging humanoid robot that scares the Internet

Few things succeed in riling up the Internet faster, unleashing a unique cocktail of amazement and terror, than a new Boston Dynamics robot video.

Love Letters: The Podcast

Love Letters Podcast

// Why can?t we be friends?

It?s easy to say you?ll remain chummy with your ex. It?s much harder to actually do.

Listen:   Apple Podcasts   |   Stitcher   |   RadioPublic


Opinion & Ideas

Ideas | Liya Rechtman

// When the apocalypse is a feature, not a bug

President Trump?s moves in the Middle East hearten an unlikely segment of his political base: Christian evangelicals steeped in apocalyptic theology.


// Business Headlines

Start the day with early-morning business, tech, and economic news Monday through Friday. Sign up here.

Breaking News Alerts

// Sign up for breaking news alerts from the Globe

Get the latest news ? from weather to Trump to local happenings ? delivered via Facebook messenger.