Is this $359m land deal the last piece of the Seaport puzzle?

Preliminary plans for buildings on the sites WS Development acquired are highlighted in the Seaport Square master plan.

WS Development.

?This is the hottest neighborhood in town,? said one developer. ?It?s an extraordinary opportunity.?

Man, 30, is shot and killed in Brighton

A man was shot and killed on Telford Street in Brighton around midnight, police said.

Hillary Clinton confronted Republican critics on the committee Thursday with a challenge to ?reach for statesmanship.?

Clinton remains unruffled during Benghazi hearing

Hillary Clinton did not appear to suffer any new political damage during the 11-hour hearing.

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2015/10/22/BostonGlobe.com/Metro/Images/massmap-8874--90x90.jpg A town-by-town look at the opioid epidemic?s toll in Mass.

Some communities have been hit particularly hard by the epidemic.

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2015/10/22/BostonGlobe.com/Metro/Images/23opioid02.jpg Police back Baker?s plan to battle opioid crisis

The controversial legislation would give hospitals new power to force treatment for up to 72 hours on some substance abusers.

Julie Burros, Boston?s chief of arts and culture, said of the shifts: ?I?m not panicking. I know a lot of people are panicking. I have been working with everyone involved.?

Pat Greenhouse/Globe Staff

Shirley Leung

Boston needs to be in the spotlight amid arts upheaval

Julie Burros, Boston?s chief of arts and culture, has been oddly silent during the turmoil in the city?s theater industry.

Jeff Schwartz and Mandy on an outing to the Esplanade this month. After his devastating accident, Schwartz  rescued a dog and his own way of living.

Wendy Maeda/Globe Staff

In a blissful life upended, the gift of man?s best friend endures

After losing his leg and beloved mini-labradoodle in a devastating accident, Jeff Schwartz rescued a dog ? and his own way of living.

Paul Ryan took several major steps Thursday to fill a leadership void in a fractured Republican Party.

Prospects uncertain for GOP unity under Ryan

It?s unclear whether Paul Ryan will have success in corralling representatives who want to use government shutdowns as leverage.

BEN VOLIN | ON FOOTBALL

Patriots defy convention on offensive line and at cornerback

The offensive linemen are constantly in rotation, while the cornerbacks are inexperienced and inexpensive.

Jets at Patriots, Sunday at 1 p.m.

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2015/10/22/BostonGlobe.com/Sports/Images/Tlumacki_patriotspractice_sports102a.jpg Devin McCourty doesn?t have calls go against him often

Prior to Sunday, the most recent time McCourty had been flagged for pass interference was Oct. 7, 2012.

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2015/10/22/BostonGlobe.com/Sports/Images/farrell150-8036.jpg Red Sox manager John Farrell?s cancer is in remission

Farrell received the good news following a post-treatment scan at Massachusetts General Hospital.

DAVID L. RYAN/GLOBE STAFF

Widett Circle businesses fume at exclusion from development talks

Some are objecting to a discussion next week that failed to include any of the 22 Widett-based businesses on the panel.

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2015/10/22/BostonGlobe.com/Metro/Images/ryan_dinocaged6_met-001.jpg Cranky fugitive cockatoo captured in Brookline

Dino, an irascible cockatoo who spent the summer terrorizing Robert F. Kennedy?s childhood home, is finally back in his cage.

Art Review

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2015/10/16/BostonGlobe.com/ReceivedContent/Images/WhataLoving,andBeautifulWorld6.jpg Japanese collective teamLab enchants at Radcliffe

In ?What a Loving and Beautiful World,? the Japanese arts and technology consortium teamLab mixes ancient art and modern technology in entrancing ways.

?This house is one of the most important historic buildings in Framingham,? said Janice Thompson of the The Sarah and Peter Clayes House Preservation Project.

Framingham ?witch house? may finally get new owner

The structure, which dates to the Salem witch trials, has been vacant for more than a decade and is in dire condition.

Opinion & Ideas

Dr. Diane E. Meier

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2015/10/22/BostonGlobe.com/EditorialOpinion/Images/1023hands2.jpg How to get what we need at the end of life

In order to know what our patients prize most, we need to ask them, and then we must be able to act on what we learn.

Ground Game

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2015/10/19/BostonGlobe.com/Politics/Images/68a240375dff4158b5e6199fadfd6b13-68a240375dff4158b5e6199fadfd6b13-0-126.jpg Webb would effectively end bid with independent run

If Jim Webb runs as an independent, he will run without any built-in fund-raising and political infrastructure from the party.

The Big Picture

Pale light hangs in a pine forest during a rainy autumn morning on Oct. 15, near Fuerstenwalde, eastern Germany.

Patrick Pleul/AFP/Getty Images

Autumnal hues around the world

Before bleak scenes and colder temperatures arrive, foliage and glowing sunsets enliven landscapes across the globe.

BetaBoston

BetaBoston

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2015/10/21/BostonGlobe.com/Business/Images/maeda_20phonebooths-downpage_biz1.jpg The phone booth makes a comeback

Superman?s go-to changing room is making a comeback in open offices, providing needed privacy in workspaces designed for collaboration.

Crux

//c.o0bg.com/rf/image_90x90/Boston/2011-2020/2015/10/21/BostonGlobe.com/Foreign/Images/2015-10-21T120859Z_966186651_GF20000026188_RTRMADP_3_POPE-VATICAN[1]-982--90x90.jpg Vatican denies report that Pope Francis has brain tumor

The Vatican said the pope is in good health and that his head is ??absolutely perfect.??