Seeing the light in cancer story

Seth Rogan (left) and Will Reiser (pictured at the Four Seasons Hotel) became friends while working on “Da Ali G Show” eight years ago. Their response to Reiser’s past cancer diagnosis is the basis of “50/50,” a film written by Reiser and starring Rogen.

Suzanne Kreiter/Globe Staff

Seth Rogen helps turn his friend’s screenplay into comedy-drama “50/50.”

Emily and Jake Steinmann, at a dance class in Newton, were happy to find out that even if they need to put off buying a house, starting a family could be affordable.

MONEY MAKEOVER

Aggressive approach will pay off with loans

Emily and Jake Steinmann applied for a Boston Globe Money Makeover, saying that their limited financial planning experience was no match for their nearly $190,000 of student loan debt.

Boston Red Sox's Jacoby Ellsbury, left, Jason Varitek and Dustin Pedroia, right, react during the eighth inning of the first game of a baseball doubleheader against the New York Yankees, Sunday, Sept. 25, 2011, at Yankee Stadium in New York. The Yankees defeated the Red Sox 6-2. (AP Photo/Bill Kostroun)

YANKEES 6, RED SOX 2

Boston’s slide continues

The Red Sox lost in the first game of a doubleheader for the team’s 18th loss this month, and the Rays won, leaving the Sox only a half-game up in wild-card race.

Mapping effects of change in Vt.

The University of Vermont is studying more than 36,000 photos of Interstate 89’s construction to learn how the interstate highway system changed Vermont.

Jeff Jacoby

Climate skeptics don’t ‘deny science’

Someday the workings of climate change may be as well understood as plate tectonics. Until then, scientific findings will be overstated by people with political and social agendas.

Buffalo Bills' Stevie Johnson (13) makes a touchdown catch under pressure from New England Patriots' Devin McCourty (32) during the first half of an NFL football game in Orchard Park, N.Y., Sunday, Sept. 25, 2011. (AP Photo/Gary Wiepert)

AP

BILLS 34, PATRIOTS 31

Patriots can’t hold on

New England had a 21-0 lead in the second quarter but couldn’t withstand an offensive surge by Buffalo, which won it with a field goal as time expired.

Metro

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Starts & Stops

The ‘last’ unrestricted Cambridge block? Not quite

The neighborhood once had swaths of unpoliced spaces, but they have been removed block by block as MIT and the area’s tech businesses have flourished.

Business

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INNOVATION ECONOMY

The Prodigy infant car seat is the first with a diagnostic display to guide proper installation.

Three-year incubation results in a smart car seat

A Woonsocket, R.I., company, Summer Infant Inc., wanted to develop a car seat that would be foolproof for a novice to install properly.

Nation

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President Barack Obama.

Obama’s small donors hold off on contributions

In recent months, the frustration and disillusionment that have dragged down President Obama’s approval ratings have crept into the ranks of his vaunted small-donor army.

Sports

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BILLS 34, PATRIOTS 31

Buffalo Bills' Stevie Johnson (13) makes a touchdown catch under pressure from New England Patriots' Devin McCourty (32) during the first half of an NFL football game in Orchard Park, N.Y., Sunday, Sept. 25, 2011. (AP Photo/Gary Wiepert)

Patriots can’t hold on

New England had a 21-0 lead in the second quarter but couldn’t withstand an offensive surge by Buffalo, which won it with a field goal as time expired.

Arts

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The BSO opens its new season on Friday.

Who will pick up the baton?

As the Boston Symphony Orchestra sets out on its search for the next music director, questions have been swirling about the process and what the public can expect.

Travel

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Opinion

“By now, only ideologues and political propagandists insist that all reputable scientists agree on the human responsibility for climate change.”

Jeff Jacoby 

Ideas

“Could it be true, Pinker wondered, that humans had actually become less violent with time, as opposed to more? And if so, how had we done it?”

Leon Neyfakh,   on Steven Pinker’s new book about violence in history