Patrick defends Murray on calls

Governor Deval Patrick insisted that Lieutenant Governor Timothy P. Murray was only doing his job in talking frequently with former Chelsea Housing director Michael E. McLaughlin.

Casino bill includes $50m for health care overhaul

Legislative leaders said the money may be used to buy new computers and software that will enable providers to better coordinate patients’ care and track costs.

debee tlumacki for the boston globe

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Drawn to her animals

Author Jan Brett shares her life with a BSO bassist, a lot of chickens, and a wild imagination.

Saugus, MA -- 11/18/11 -- Val Struzziero, breast cancer survivor, poses for a portrait in her home in Saugus, MA on November 18, 2011. (Kayana Szymczak for the Boston Globe)

Kayana Szymczak for The Boston Globe

FDA revokes approval of Avastin for breast cancer

The agency based its decision on studies concluding that the drug didn’t improve the quality of life nor extend the lives of women with metastatic breast cancer.

Editor steers church paper into controversy

A former European lay missionary, Antonio Enrique is now editor of The Pilot and a target of criticism for articles that have opened old wounds for the church.

Parents of troubled adults face dilemmas

Responding to threatening behavior by adult children with mental illnesses has long been a quandary, but it has become all the more so in the aftermath of the recent murders in Weymouth and Danvers.

Community colleges dispute call for overhaul

Community college presidents reacted with surprise yesterday to a Boston Foundation report recommending a structural and financial overhaul of their system.

Metro

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Boston, MA 111811 Boston Police detectives, near the scene of a multiple shooting on Warrenton Street last night, search the area(far right) and interview a civilian, seated far left, in Boston's Theatre District, Friday, November 18 2011. (Globe Staff Photo/Wendy Maeda) section: Metro slug: 19shooting reporter: Brian Ballou

Boston board asks nightclub to close after shootings

Boston’s licensing board has asked a Theatre District nightclub to close pending a hearing, after four people were shot in what police called a gang-related incident near the establishment.

Business

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MIT begins building Pfizer facility

The 230,000-square-foot building will house research operations focused on developing cures for illnesses ranging from type 2 diabetes, to Alzheimer’s, to schizophrenia.

Politics

R After a screening of a documentary he produced with his wife that promotes American exceptionalism, GOP candidate Newt Gingrich said he has been stunned by his rise in the polls.

Gingrich says firm took funds

At an event in Harvard University last night, Republican presidential candidate Newt Gingrich distanced himself from payments his consulting firm collected from Freddie Mac.

Nation & World

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Protesters criticized, among other things, proposals that would protect the military from civilian scrutiny of its budget.

Islamists challenge Egyptian military rule

Tens of thousands of Islamists jammed Tahrir Square yesterday in the most significant challenge yet to the authority of the country’s ruling military council.

Sports

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Red Sox throw a changeup in their search

The Red Sox had a clear model in mind when they set out to replace Terry Francona in the early days of October. Bobby Valentine did not fit those well-considered parameters.

Special reports